Understanding Substance Induced Psychosis

What Is Psychosis?

Substance-induced psychosis is a serious but treatable condition in which a person temporarily loses touch with reality following the use of alcohol or other mood-altering substances. While the experience can be frightening for both the individual and their loved ones, early treatment and sustained recovery can lead to excellent outcomes.

Common Symptoms

The symptoms of psychosis vary from person to person but often include the following. Not everyone will experience every symptom, and the severity can vary considerably from one person to another.

Hallucinations: False sensory experiences that occur while a person is awake. They may involve seeing, hearing, smelling, tasting, or feeling things that are not actually present. Hearing voices (auditory hallucinations) is one of the most common forms and can be extremely frightening.

Delusions: Fixed false beliefs that persist despite clear evidence to the contrary. A person may believe they are being watched, followed, plotted against, or poisoned. Others may believe a loved one has been replaced by an impostor or believe, without evidence, that their partner is being unfaithful.

Persecutory Delusions: Sometimes accompanied by auditory hallucinations, such as hearing voices that appear to confirm the person’s fears or reinforce their false beliefs. The combination of hearing threatening voices and believing that others intend to cause harm can be overwhelming and extremely distressing.

It is important to remember that these experiences are symptoms of an illness affecting the brain’s ability to interpret reality accurately. They are not a sign of weakness, a character flaw, or a lack of intelligence. For the person experiencing psychosis, these voices and beliefs feel completely real, even though they are not based in reality.

Thought Disorders: Difficulty organising thoughts, concentrating, following conversations, or expressing ideas clearly. Speech may become disorganised or difficult for others to follow.

Changes in behaviour: Becoming withdrawn, isolating from family and friends, suspicious, confused, behaving in ways that are unusual or out of character, and in some cases becoming agitated or aggressive.

What Causes Psychosis?

Although psychosis can occur in several mental health and medical conditions, this article focuses on psychosis triggered by alcohol or other mood-altering substances. Substance use can either trigger a first episode of psychosis or worsen an existing vulnerability, particularly in people with underlying mental health conditions or a family history of psychotic illness. Although stimulant drugs and cannabis are well-known triggers, severe alcohol intoxication and alcohol withdrawal can also cause psychotic symptoms in some individuals.

Psychosis Vulnerability

A person who has experienced substance-induced psychosis is much more likely to experience further psychotic episodes if they use drugs or alcohol again. Using alcohol or drugs places additional stress on already vulnerable brain pathways, increasing the likelihood of another psychotic episode. Symptoms often return more quickly and may become more severe than before.

Risks and Effects

  • Triggering new episodes: For people who have previously experienced substance-induced psychosis, returning to alcohol or drugs significantly increases the risk of another episode. In many cases, symptoms return more rapidly and may become more severe than before.
  • Blocking medicine: Alcohol and other drugs can interfere with prescribed mental health medications, including antipsychotic medication, making them less effective.
  • Higher chance of long-term illness: Continuing to use substances after a first episode raises the risk of developing a psychotic disorder.  

Can Psychosis Be Treated?

Some people experiencing severe substance-induced psychosis require stabilisation in a psychiatric hospital before entering addiction treatment. Once medically stable, comprehensive rehabilitation should address not only substance use but also the underlying psychological, emotional, and social factors that contribute to addiction. At Twin Rivers Recovery, we provide an individualised treatment programme that addresses trauma, co-occurring mental health conditions, substance dependence, and the development of healthier coping strategies to support long-term recovery.

A Message of Hope

Recovery from substance-induced psychosis is possible, and many people make a full recovery when they receive timely treatment, remain abstinent from alcohol and other mood-altering substances, and receive ongoing psychological support. Seeking help early can make a significant difference and offers the best chance of a successful recovery.

Frequently Asked Questions:

Can substance-induced psychosis go away? Yes. Many people recover completely with prompt medical treatment, abstinence from alcohol and drugs, and ongoing psychological support.

Can cannabis cause psychosis? Yes. In some people—particularly those with a genetic or mental health vulnerability—cannabis can trigger psychotic symptoms or worsen an existing condition.

Is substance-induced psychosis the same as schizophrenia? No. Although the symptoms can be similar, substance-induced psychosis is directly related to alcohol or drug use. However, repeated episodes may increase the risk of developing a long-term psychotic disorder in some individuals.


Disclaimer: This article is intended for educational purposes only and should not replace professional medical advice, diagnosis, or treatment. If you or someone you know is experiencing psychosis, particularly if they are at risk of harming themselves or others, seek immediate medical attention or contact your nearest emergency service.

Registered with the South African Department of Social Development under the Prevention of Treatment for Substance Abuse Act 2008
Registration No: 15/10/3/4/2-16/2024

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